A.vera leaf extract, which is rich in polysaccharides, is frequently used for burns, sunburns, wounds and skin inflammations. In a randomized study, lyophilized A.vera extract was studied on 20 volunteers and a significant increase was observed in the moistening of the skin after 2 weeks. However, there was no significant change in TEWL.

A.vera has traditionally been used for wounds, burns, insect stings and skin inflammations for centuries. It has antioxidant, anti-inflammatory, antimicrobial and immunomodulatory effects. The mamose-6 phosphate and acemannan in a. vera supports the epithelization for effective wound repair and supports collagen synthesis. A.vera is used for its wound repairing properties.

UV radiation reduces immunity to infections along with many other damages. Vitamin C, Vitamin E, flavonoids, phenolic acids fight with free radicals that cause negative changes in the skin. Therefore, the complex structures of the plants rather than the individual substances have a higher protective effect on the skin. A. vera gel revitalizes the skin and promotes the formation of new cells.

14 kDa Aloe protein was isolated using DEAE-cellulose and CM-cellulose column with ion exchange chromatography on aloe vera leaf gel. Purified Aloe protein showed antifungal activity against Candida paraprilosis, Candida crusei, and Candida albicans. Additionally, the purified Aloe protein showed anti-inflammatory action with 84% and 73% inhibition against pure lipoxygenase and cyclooxygenase-2. This Aloe protein is a new protein that shows antifungal and anti-inflammatory effects and can be used for medical purposes.

Aloe vera gel shows anti-inflammatory, repairing, moisturizing, antibacterial, antifungal and antiviral effects.

A. vera leaf extract is rich in catechin, sinapic acid and quersitrin. The extracts of the leaf also show antioxidant activity and activity against microbial strains. Phenolic compounds in the plant also prevent the diseases due to oxidative stress. There are many chemical compounds such as tannin, saponin, flavonoid, steroid, terpenoid in A.vera leaf and gel. As the phenolic compounds increase, the antioxidant effects also increase.

The claims in the studies for Aloe vera are as follows:

Aloe vera softens the skin, beta the bisabolol obtained from Chamomile has an anti-inflammatory and antibacterial effect, Calendula oil has a soothing, softening and cells renewing effect, essential fatty acids such as linoleic-linolenic smooth, moisturize and protects the skin, Panthenol moisturizes and soothes the skin.